From This Might Be A Wiki
- Here Comes Science is nominated for a 2010 Grammy for Best Musical Album for Children, but the band loses to Pete Seeger's Tomorrow's Children.
- Join Us, TMBG's fifteenth full-length album, is released on July 19. Prior to the release, four advance tracks are made available on iTunes and theymightbegiants.com on April 26.
- They Might Be Giants and Idlewild Recordings announce the They Might Be Giants Instant Fan Club: a paid subscription service for 2011 similar to TMBG Unlimited in 2001, including exclusive MP3 or FLAC downloads, a copy of TMBG's Other Thing Brass Band (EP) (both digital and vinyl), a pair of TMBG concert tickets, and several other merch items and digital goods.
- In October, the band releases two songs written for the video game Adventure Quest Worlds: The Collector.
- October 28 sees the release of Album Raises New And Troubling Questions, a rarities compilation.