Experimental Film

From This Might Be A Wiki

John and John "powered by The Cheat"

Tentacle Skull riding a Penny Farthing

song name	Experimental Film
artist	They Might Be Giants
album	The Spine, Experimental Film (Single), TMBG Clock Radio, Venue Songs (DVD/CD)
year	2004
first played	Jan. 25, 2004 (121 known performances)
run time	2:56
sung by	John Linnell

The Homestar Runner video features many of the H*R characters created by Mike and Matt Chapman. Clicking on the text "Directed by Strong Sad & The Cheat" at the beginning of the video loads an audio commentary by the H*R characters. It doesn't have much to do with TMBG lore, but they do refer to Them as "Super Giants," "Supreme Giants," and "That one right there with the glasses", and make continual references to the skull.
See the hrwiki.org entry on this song: Experimental Film.
At the November 18, 2006 show in Nyack, the song was announced as "Too Physically Weak!" and it ended with alternate lyrics: "Yeah! I'm physically weak in this experimental film..." The reason for this change is likely because it was the final song of the shows second encore. The band was indeed, tired and "physically weak".
When this song is played live, Flansburgh has a tendency to yell "Guitar!" in a falsetto voice before the solo, reminiscent of Justin Hawkins of The Darkness in "I Believe in a Thing Called Love".