Fictional characters who appear on They Might Be Giants Podcast.
| Character Name | Description | Voiced By | Appears In |
|---|---|---|---|
| Cecil Portesque | The host of TMBG's Podcast. | John Linnell* in 1A, John Flansburgh* in the rest. | All episodes from seasons 1 and 2 except Podcasts 6C, 10A, 11A, 25A, 27A, and 28A-B-C |
| Julian Dufy | TMBG's "longtime engineer and archivist." | John Flansburgh* | Podcast 10A, Podcast 11A |
| The Deranged Millionaire | Appeared out of contractual obligation, due to TMBG's completion of the Venue Songs challenge. | John Hodgman | Podcast 3A |
| David Remnikopf | Computer assisted, three dimensional special effects for the song (She Was A) Hotel Detective In The Future. | John Linnell* | Podcast 5A |
| Anne Hathaway | Foley artist for "(She Was A) Hotel Detective In The Future". | John Linnell* | Podcast 5A |
| Evan and Anderson | Band members of They Must Be Giants. | John Flansburgh* | Podcast 26A |
*The actors for these voices have not been officially confirmed by the band and will likely never be clarified. They are findings of original research, using audio editing methods such as pitch bending.